Identifying expressed genes
نویسندگان
چکیده
منابع مشابه
Identifying differentially expressed genes with siggenes
In this vignette, we show how the functions contained in the R package siggenes can be used to perform both the Significance Analysis of Microarrays (SAM) proposed by Tusher et al. (2001) and the Empirical Bayes Analysis of Microarrays (EBAM) suggested by Efron et al. (2001).
متن کاملMultivariate methods for identifying differentially expressed genes
Motivation: Univariate testing procedures remain the most common way to identify differentially expressed genes (DEGs). Univariate techniques suffer from the multiple comparison problem and reduced power, because they fail to account for gene interaction. Motivated by these issues, we adopt a multivariate procedure. Namely, we utilize the sup-norm test, which was specifically developed for high...
متن کاملStatistical methods for identifying differentially Expressed genes in microarray data
Microarray is a recently developed functional genomic technology that has powerful applications in a wide array of biological research areas, including the medical sciences, agriculture, biotechnology and environmental studies. One of the important problems in the analysis of microarray data is the identification of differentially expressed genes. Commonly used approaches for identifying differ...
متن کاملIdentifying Differentially Expressed Genes in cDNA Microarray Experiments
A major goal of microarray experiments is to determine which genes are differentially expressed between samples. Differential expression has been assessed by taking ratios of expression levels of different samples at a spot on the array and flagging spots (genes) where the magnitude of the fold difference exceeds some threshold. More recent work has attempted to incorporate the fact that the va...
متن کاملNonparametric methods for identifying differentially expressed genes in microarray data
MOTIVATION Gene expression experiments provide a fast and systematic way to identify disease markers relevant to clinical care. In this study, we address the problem of robust identification of differentially expressed genes from microarray data. Differentially expressed genes, or discriminator genes, are genes with significantly different expression in two user-defined groups of microarray exp...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2000
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.97.8.3789